168 Figure 4 (A-B) | Enriched IgG-coated fecal bacterial genera in patients with IBD and HC. (A) Schematic illustration of the IgG-based MACS-sorting procedure. The total fraction (top) represents the original, untreated sample, while the IgG-coated fraction represents the fraction left after magnetic separation of the non-IgG-coated bacterial fraction (negative fraction). (B) The bacterial genera Streptococcus, Coprococcus, Dorea, Lactobacillus, Dialister, Veillonella, and Turicibacter as well as R. gnavus-like bacteria were significantly enriched in IgG-coated samples in both patients with IBD and HC. Lactococcus bacteria were significantly enriched after IgG-coating solely in patients with IBD and Clostridium, Enterococcus and Collinsella solely in HC. Bold indicates bacterial genera that were significantly more enriched in IBD vs. HC. Chapter 5
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