162 Figure 1 (A-B) | Microbial richness and evenness of fecal samples from patients with IBD (orange colored) and HC (blue colored). (A) The number of OTUs was significantly lower in fecal samples from patients with IBD compared with samples from HC. OTUs were not significantly different after IgGcoating in samples from HC, whereas there was a small decrease in IgG-coated vs. untreated fecal samples from patients with IBD (paired analysis, P<0.001). (B) The Shannon diversity index, representing the alpha-diversity of the gut microbiota, was significantly lower in patients with IBD vs. HC. Similar to the OTUs, IgG-coated vs. untreated samples showed no significant change in Shannon diversity index among HC, whereas there was a small decrease observed in IgG-coated samples from patients with IBD. Abbreviations: HC, healthy controls; IBD, inflammatory bowel disease; MACS, magnetic-activated cell sorting; OTUs, operational taxonomic units ;ns, non-significant. ***P<0.001..
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