159 Results Cohort characteristics We included 55 patients with IBD (34 CD, 17 UC and 4 IBD-U) and 55 healthy controls (HC) (Table 1). Mean age was 44 (range: 20-64) years for patients with IBD and 46 (range: 20-64) years for HC. Among patients with IBD, 60% were female, which was comparable to 53% females among HC. Most patients with IBD were in clinical remission at the time of sampling (76%), whereas approximately one fourth of patients had active disease (24%). Table 1 | Demographic and clinical characteristics of the study population Table 1. Demographic and clinical characteristics of the study population. IBD HC P-value Age (years) 45 [32;54] 48 [36;59] 0.454 Sex, n (%) 0.442 Male 22 (40.0%) 26 (47.3%) Female 33 (60.0%) 29 (52.7%) IBD type, n (%) CD 34 (61.8%) - UC 17 (30.9%) - IBD-U 4 (7.2%) - Montreal classification Montreal Age (A) A1 (≤ 16 years) 4 (7.2%) - A2 (17-40 years) 27 (49.1%) - A3 (> 40 years) 22 (40.0%) - Montreal Location (L), CD L1 (ileal disease) 13 (38.2%) - L2 (colonic disease) 11 (32.4%) - L3 (ileocolonic disease) 10 (29.4%) - Montreal Behavior (B), CD B1 (non-stricturing, non-penetrating) 23 (67.6%) - B2 (stricturing) 7 (20.6%) - B3 (penetrating) 4 (11.8%) - Montreal Perianal disease (P), CD 3 (8.8%) - Montreal Extension (E), UC E1 (proctitis) 3 (17.6%) - E2 (left-sided colitis) 4 (23.5%) - E3 (pancolitis) 10 (58.8%) - Montreal Severity (S), UC S0 (remission) 4 (23.5%) - S1 (mild) 4 (23.5%) - S2 (moderate) 3 (17.6%) - Antimicrobial IgG immune responses in IBD
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