141 Supplementary Table S14. Differentially abundant antibody-bound peptides between patients with ileal IBD (Montreal L1/L3) and patients with solely colonic IBD (Montreal L2/E). Supplementary Table S15. Differentially abundant antibody-bound peptides between patients with stricturing CD (Montreal B2) and non-stricturing, non-penetrating CD (Montreal B1). Supplementary Table S16. Differentially abundant antibody-bound peptides between patients who had a history of ileocecal resection (ICR) and those who did not have a past ICR. Supplementary Table S17. Differentially abundant antibody-bound peptides between patients who had a history of (partial) colon resections and those who did not have previous colon resections. Supplementary Table S18. Differentially abundant antibody-bound peptides between patients who had IgG antibodies against Saccharomyces cerevisiae (ASCA) at time of sampling. Supplementary Table S19. Differentially abundant antibody-bound peptides between patients who had IgA antibodies against Saccharomyces cerevisiae (ASCA) at time of sampling. Supplementary Table S20. Differentially abundant antibody-bound peptides between patients who had anti-neutrophil citrullinated antibodies (ANCA) at time of sampling. Supplementary Table S21. Analysis of sequence homology between well-established antiflagellin antibodies (anti-A4-Fla2, anti-Fla-X, anti-CBir1 and anti-OmpC) in IBD and anti-bound peptides as analyzed by PhIP-Seq. Supplementary Table S22. Associations between microbial taxa (derived from metagenomics shotgun sequencing [MGS] data) and antibody-bound peptides (logistic regression analysis after partialling out effects of age and gender). Supplementary Table S23. Permutational multivariate analysis of variance (PERMANOVA) or ADONIS analysis demonstrating the explained variance in antibody-bound peptides by different microbial taxa derived from MGS. Supplementary Table S24. Associations between dysbiosis scores (based on Bray-Curtis dissimilarity indices) and the presence of antibody-bound peptides. The antibody epitope repertoire in IBD
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