Thesis

62 A power analysis was conducted, with an expected ICC of at least 0.7. A p1 value of 0.9 was chosen, therefore the sample size had to be at least 18.4.27 Data were tested for normality using a Shapiro-Wilk test. Because data were not normally distributed, a Wilcoxon Signed Ranks test was conducted to examine differences between the test outcomes of the WST for both patients with HNC and healthy subjects. A paired samples t-test was conducted to examine differences between the number of swallows reported by the researcher in comparison to the number of swallows reported by the patient or healthy subject. A Kruskal-Wallis test was conducted to examine differences in WST outcomes according to sex and age. All analyses were performed using Statistical Package for the Social Sciences (SPSS) version 25 (Chicago, IL). A p-value below 0.05 was considered statistically significant. Results Thirty-three patients with HNC and 40 healthy subjects performed the WST twice on the same day. In Table 1, subject characteristics are depicted for patients with HNC and healthy subjects. The median age for patients with HNC was 65 years (91% male), and 31 years (50% male) for healthy subjects. All subjects were able to drink the 100 mL of water, and no missing data were reported. For the patient group, ten patients performed the test before treatment, five patients 3 months after treatment, five patients 6 months after treatment, five patients 12 months after treatment, and eight patients 24 months after treatment. No significant differences (p=1.00) were reported between number of swallows reported by the researcher (mean=4.25, SD=2.41) in comparison to the subject (mean=4.25, SD=2.43). Significant differences were found for age and sex between patients with HNC and healthy subjects (p<0.001 and p=0.002, respectively). Mean and median scores are depicted in Table 2 for patients with HNC and healthy subjects, and for test and retest.

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