98 Appendix 7. Spearman correlation coefficients of salivary flow versus the EORTC QLQH&N35 *: p<0.05, M0: before treatment, M3: 3 months after treatment, M6: 6 months after treatment Salivary flow EORTC QLQ-H&N35 M0 (n = 45) M3 (n = 68) M6 (n = 59) Spearman’s ρ p-value Spearman’s ρ p-value Spearman’s ρ p-value Pain in mouth -0.100 0.503 -0.171 0.153 -0.048 0.718 Swallowing -0.050 0.737 -0.167 0.164 0.073 0.579 Senses problems -0.450 0.002* -0.272 0.022* -0.287 0.026* Speech problems 0.037 0.803 0.057 0.635 0.168 0.199 Trouble with social eating -0.051 0.735 -0.292 0.014* -0.238 0.067 Trouble with social contact -0.179 0.228 -0.102 0.397 -0.008 0.950 Less sexuality -0.024 0.875 -0.008 0.950 -0.181 0.171 Teeth 0.042 0.778 -0.034 0.775 -0.091 0.493 Opening mouth -0.188 0.207 -0.174 0.146 0.093 0.479 Dry mouth -0.227 0.126 -0.339 0.004* -0.279 0.031* Sticky saliva -0.217 0.143 -0.321 0.006* -0.350 0.006* Coughing -0.300 0.040* -0.022 0.853 -0.074 0.572 Feeling ill -0.125 0.403 0.024 0.843 0.124 0.351 Pain killers 0.011 0.940 0.056 0.645 -0.133 0.310 Nutritional supplements -0.390 0.007* -0.314 0.008* -0.162 0.215 Feeding tube -0.196 0.187 -0.189 0.114 NA NA Weight loss -0.038 0.805 -0.105 0.384 -0.267 0.041* Weight gain -0.185 0.219 0.059 0.627 -0.127 0.335
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