Thesis

97 Markers of neurodegeneration in subjective cognitive decline Concluding, correlations between different N biomarkers were low in a sample of cognitively normal individuals, indicating they may not reflect the same underlying pathology. T-tau was strongly associated with p-tau, and thereby disqualified as measure for N in this context. Our results show HV, NfL and GFAP predicted clinical progression, and have added value beyond Aβ and p-tau. However, our results do not allow to choose one most suitable biomarker for N. 4

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