37 ATN classification in subjective cognitive decline Table 4. Relationship between ATN biomarker profiles and baseline and longitudinal cognition (continued) Baseline Longitudinal A-T-N+ A-T+N- A-T+N+ A+T-N- A+T-N+ A+T+N- A+T+N+ A-T-N+ A-T+N- A-T+N+ A+T-N- A+T-N+ A+T+N- A+T+N+ Stroop I -0.01 (0.04) -0.00 (0.02) -0.02 (0.07) 0.01 (0.04) -0.01 (0.06) -0.00 (0.03) -0.03 (0.07) -0.00 (0.02) 0.00 (0.01) -0.00 (0.02) -0.02 (0.01) 0.03 (0.05) -0.02 (0.01) -0.04 (0.03) Stroop II -0.02 (0.04) -0.01 (0.02) -0.08 (0.06) -0.04 (0.04) -0.03 (0.06) -0.02 (0.03) -0.08 (0.07) 0.00 (0.02) -0.00 (0.01) -0.03 (0.03) -0.04 (0.01) -0.02 (0.04) -0.02 (0.01) -0.05 (0.03) Stroop III -0.01 (0.04) -0.00 (0.03) -0.01 (0.08) -0.01 (0.04) -0.21 (0.07) a 0.03 (0.04) -0.08 (0.08) 0.00 (0.02) -0.00 (0.01) -0.06 (0.04) -0.04 (0.02) -0.01 (0.07) -0.05 (0.02) a -0.07 (0.04) Abbreviations: RAVLT=Rey Auditory Verbal Learning Test; TMT=Trail Making Test; VAT=Visual Association Test. Values given are β (SE), corrected for age, sex, education, as estimated by linear mixed models (reference category: A-T-N-). β baseline = association between ATN category and baseline test result. β longitudinal = association with annual decline. Note that TMT-A, TMT-B, Stroop I, Stroop II, Stroop III are log transformed and inversed. a p-value remaining significant after false discovery rate correction with q set at 0.05 2
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