146 Chapter 6 Figure 3. Visualization of trajectories of BPND over time Spaghetti plots showing individual trajectories of BPND over time (A Frontal, B Temporal, C Parietal, D Occipital, E Composite regions). For visualization, the sample was divided into tertiles. Separate lines represent R1 tertiles (based on baseline values). BPND and R1 are z-transformed.