Thesis

138 PART THREE | DELIRIUM On day 2, delirium assessment with DRS-R-98 is repeated. Resolution of delirium was defined as a DRS-R-98 total severity score of <15.25 points with a ≥4.5 points reduction in the severity items scores. If on day 3 the severity score of DRS-R-98 is ≥15.25 points, maintenance dose of haloperidol is increased according to the following guideline. Haloperidol Day 3: maintenance dose Total dose (mg) day 2* Evening dose (mg) Morning dose (mg) Rescue dose (mg; maximum twice daily) Total dose (mg) day 3** 1.5 1 1 1 4 2 2 1 1 5 2.5 2 2 2 8 4 2.5 2.5 2 9 4.5 3 3 2 10 6 4 4 2 12 6.5 4 4 2 12 8 5 5 2.5 15 8.5 5 5 2.5 15 10 6 6 3 18 10.5 6 6 3 18 12 7 7 3 20 12.5 7 7 3 20 14 7.5 7.5 2.5 20 14.5 7.5 7.5 2.5 20 16 8 8 2 20 16.5 8.5 8.5 1.5 20 18 9 9 1 20 18.5 9.5 9.5 0.5 20 20 10 10 0 20 *Total dose ended .5 are rounded up **With maximum use of rescue dose

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