96 CHAPTER 4 Table 4. Adverse events (n = 51) Total amount of AE, n (%) 16 (31.4%) AE, n (%) 12 (24.0%) Postoperative bleeding, n (%) 1 (2.0%) Prolonged antibiotics for a floor-of-mouth cyst, n (%) 1 (2.0%) Diminished feeding due to nausea, n (%) 1 (2.0%) Prolonged pain medication, n (%) 2 (3.9%) Antibiotics for pneumonia, n (%) possibly related to the intervention 2 (3.9%) Xerostomia, n (%) 2 (3.9%) Swelling of the submandibular region, n (%) 2 (3.9%) Dysphagia, n (%) 1 (2.0%) ^ SAE, n (%) 4 (7.8%) Direct postoperative admission due to nausea, n (%) related to the intervention 1 (2.0%) Admission due to nausea, n (%) unrelated to the intervention 1 (2.0%) ^ Admission because of dehydration due to gastroenteritis, n (%) 1 (2.0%) ^ Bilateral sublingual gland excision due to bilateral ranula, n (%) related to the intervention 1 (2.0%) 2-DL = two-duct ligation; AE = Adverse Event; SAE = Serious Adverse Event; ^ = unrelated to the intervention A comparison between predictors for treatment success and objective (DQ) treatment success The predictors associated with objective treatment success (DQ only) were identical to the ones identified for combined treatment success (VAS and/or DQ). DISCUSSION The purpose of this study was to identify predictors for treatment success. We found age (more mature), adequate posture (no anteflexion), and normal speech (no VSSD) to increase the chance of successful treatment of anterior drooling. Approximately 40% of children show no clinical response to 2-DL. Although multiple etiological variables have been identified for drooling (dysfunctional oral
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