91 An evaluation of predictors for success of 2-duct ligation for drooling in neurodisabilities 4 The effect of 2-DL was analyzed by comparing baseline DQ, VAS, DS and DF scores to the scores at 32 weeks. Paired sample t tests were used for the continuous variables (VAS and DQ), and a Wilcoxon rank test was used for the categorical variables (DS and DF, table 3). The level of significance was set at ≤ 0.05 except for the logistical regression analyses where the level of significance was set at ≤ 0.25 because of the small sample size of the cohort. We present odds ratios and 95% Confidence Intervals (CIs). Data availability Anonymous demographics and data will be shared on request from any qualified investigator. RESULTS Fifty-four patients were screened for eligibility. One patient was excluded due to missing baseline primary outcome data and two patients were excluded due to missing primary outcome data at 32 weeks follow-up. One patient was excluded because of a bilateral sublingual gland excision following bilateral ranula formation (SAE), because surgery interfered with salivary secretion and therewith reliable evaluation of 2-DL effect. This patient was not excluded from the AE analyses. Ten patients were excluded from the primary analyses (logistic regression) due to missing independent variables. Forty patients were left for logistic regression analyses. The mean age at surgery was 12.1 years (Standard Deviation [SD] = 3.5, ranging 8 to 23 years old), the mean interval between baseline measurement and surgery was 143.4 days (SD = 115.9), and the predominant main diagnosis was cerebral palsy (58%) versus other neurodevelopmental disabilities (genetic [no craniofacial], syndromic, not specified disorders) (42%). Additional patient characteristics are presented in table 1.
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