74 CHAPTER 3 (mean 66) (mean difference −33, F[1,113]=41.279, p≤0.001; 95% CI=−43.3 to −22.9. There was no significant difference in drooling quotient at the 8-week (mean 10.9) and 32-week (mean 14.6) follow-up (mean difference 4.7, F[1,106]=1.757, p=0.188; 95% CI=−2.31 to 11.65) and no significant difference in drooling quotient scores at follow-up between BoNT-A injection (mean 14.6) and bilateral submandibular duct ligation (mean 11.3) (mean difference 3.3, F[1,106]=0.558, p=0.457; 95% CI=−4.35 to 9.62), as illustrated by Figure 2. Figure 1: Mean Visual Analogue Scale (VAS) over time after botulinum neurotoxin A (BoNT-A) and bilateral submandibular duct ligation with 95% confidence intervals. Figure 2: Mean drooling quotient over time after botulinum neurotoxin A (BoNT-A) and bilateral submandibular duct ligation with 95% confidence intervals.
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