Thesis

71 Submandibular Duct Ligation After Botulinum Neurotoxin A Treatment of Drooling in Children With Cerebral Palsy 3 RESULTS Of the children in our centre treated with BoNT-A injections for severe drooling, 33 subsequently underwent bilateral submandibular duct ligation and were eligible for inclusion. Two children were excluded due to the concurrent use of benzodiazepines. In one child, treatment success with BoNT-A was not measured because treatment and follow-up took place at another centre; another patient was excluded because the time between BoNT-A treatment and bilateral submandibular duct ligation exceeded 5 years. Fifteen children were diagnosed with CP; the other 14 children had non-progressive developmental disorders either unexplained or mainly as part of a syndrome (e.g. Dandy–Walker, de Grouchy), genetic (e.g. trisomy 1q), or metabolic disorder. The characteristics of the 29 children included in the study (15 males, 14 females) are shown in Table 2.

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