53 Randomized controlled trial comparing botulinum versus surgery for drooling in neurodisabilities 2 DQ The DQ at follow-up was 9.3% lower after 2-DL when compared to BoNT-A (figure 3, table 2). For both interventions, the DQ was significantly (difference 7.3%, p = 0.007, CI 95% 2.1 - 12.5%) higher at the 32-week interval than after the 8-week interval. This increase did not significantly differ between the two interventions. There was a strong correlation between the regular, unblinded DQ, and the ‘blinded DQ’ that was based on video recordings. Furthermore, outcomes and significance for the mixed model analyses and response to treatment analyses when imputing ‘masked DQ’ instead of unmasked DQ were similar. Figure 3 Drooling Quotient BoNT-A = Botulinum neurotoxin type A; 2-DL = 2-duct ligation
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