199 DS, and DF. Tertiary outcomes include oral hygiene as evaluated by sequencing of salivary samples before surgery, at 8 and 32 weeks. Nature and extent of the burden and risks associated with participation, benefit andgrouprelatedness: Participantsof our studywill, as routineclinical care, visit the Radboudumc pre-operatively for initial assessment. Routine assessment includes VAS, DQ, DS, DF and salivary samples. One additional telephone survey will be obtained two weeks after treatment to evaluate post-operative complaints and adverse events. Patients or caregivers will complete a two-week complaints survey.
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