Thesis

177 Unsuccessful submandibular duct surgery for anterior drooling: Surgical failure or parotid gland salivation? 8 Furthermore, SMGE did not result in a significant reduction, from 30.6 (18.9) at baseline to 26.1 (23.0) and 29.0 (19.6) after respectively 8- and 32-weeks followup. Repeating the mentioned design with the VAS score as the within-participants variable also showed no significant difference over time (Hotelling’s trace: F=2.546; df 1, 18; p=.128). From a baseline value of 67.3 (32.5) the VAS score reduced to 57.3 (28.5) after 32 weeks. Table 3. Effect on anterior drooling after re-intervention Pat. No. Re-intervention Change in DQ (%)* Change in VAS (%)* Saliva viscosity* Drooling Severity* Drooling Frequency* Submandibular gland excision 1 SMGE - 20 (36%) - 9 (9%) Reduced Similar Similar 2 SMGE 0 - 10 (11%) Similar Similar Similar 3 SMGE - 32 (64%) - 35 (44%) Increased Similar Decreased 4 SMGE + 1 - 59 (74%) Similar Similar Similar 5 SMGE + 9 + 39 Similar Increased Increased 6 SMGE + 1 - 16 (17%) Increased Increased Increased 7a1 SMGE + 30 + 10 Reduced Similar Similar Parotid duct ligation 7b1 2PDL - 60 (85%) - 81 (91%) Increased Decreased Decreased 8 1PDL - 5 (9%) + 10 Increased Similar Decreased 9 1PDL + 5 + 10 Similar Similar Increased 10 1PDL + 2 - 25 (33%) Similar Similar Decreased Table 3 1 = 7a and 7b are the same patient. Patients in Bold: Responder (at least 50% reduction of DQ or VAS compared to baseline). SMGE: submandibular gland excision, 1PDL: unilateral parotid duct ligation, 2PDL: bilateral parotid duct ligation. a = At 32 weeks compared to baseline. PDL as a re-intervention Only the patient who underwent bilateral parotid duct ligation met the criterion for treatment success and showed a significant reduction compared to baseline in DQ (85%) and in VAS-score (91%) (Table 3, Figure 1B). This success was also reflected in the drooling severity and frequency scale. Within subject analyses showed no significance over time for 50% decrease on DQ or VAS at 32 weeks.

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