Thesis

153 The medium to long-term effects of two-duct ligation for excessive drooling in neurodisabilities, a cross-sectional study 7 Patient characteristics Characteristic Patients (n=42) Age at time of 2-DL, mean ± SD (range) 11.7 ± 3.3 (8.0 ‒ 22.6) Current age, mean ± SD (range) 17.4 ± 4.6 (11.0 ‒ 28.0) Sex, n (%) Male 24 (57.1) Female 18 (42.9) Diagnosis, n (%) Cerebral palsy 25 (59.5) Other 17 (40.5) GMFCS level, n (%)† (n=25) I 0 (0) II 2 (8.0) III 2 (8.0) IV 10 (40.0) V 11 (44.0) Ambulant (n=42) Yes 15 (35.7) No 27 (64.3) Developmental age, n (%) <4 y 25 (59.5) >4 y 14 (33.3) Unknown 1 (2.4) Reflux, n (%) Yes 13 (31.0) No 27 (64.3) Unknown 2 (4.8) Intake, n (%) Oral 21 (50.0) Gastrostomy 13 (31.0) Oral and gastrostomy 8 (19.0) Baseline measurements VAS (SD) 82.3 (12.4) DS‡ (range) 4.7 (3 – 5) DF‡ (range) 3.5 (2 – 4) Form of ligation, n (%) Clips 38 (90.5) Ligatures 4 (9.5) Total n (%) of additional treatment 14 (33.3) Invasive 13 (31.0) Unilateral parotid duct ligation (1PDL) 1 (2.4) Bilateral BoNT-A parotid gland 1 (2.4) SMGE 6 (14.3) 1. SMGE; 2. Glycopyrrolate 2 (4.8) 1. SMGE; 2. Bilateral parotid duct ligation (2PDL) 1 (2.4) 1. Bilateral BoNT-A parotid gland; 2. 1PDL 1 (2.4) 1. Glycopyrrolate; 2. bilateral BoNT-A parotid gland 1 (2.4) Glycopyrrolate monotherapy 1 (2.4) Table 1: patient characteristics at time of the survey (unless otherwise specified) †GMFCS: Gross motor function classification system (GMFCS I-III are classified as ambulant, GMFCS IV and V as non-ambulant); measured for patients with CP. ‡Baseline and 8 week DS and DF were missing in 1 patient.

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