107 Surgery vs botulinum for the impact of drooling on daily life in children with neurodevelopmental disabilities: a randomized controlled trial 5 2-DL, there was a significantly larger and longer-lasting positive effect on most of the outcomes in this study compared to BoNT-A. What this paper adds: • Bilateral botulinum neurotoxin type A (BoNT-A) and submandibular duct ligation have a positive effect on the well-being. • Bilateral submandibular duct ligation has a larger effect on the impact of drooling on daily care, reducing damage to electronic devices and improving social interaction and satisfaction with life.
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