70 Chapter 3 Effective triptan response Considering only migraine days with an effective triptan response instead of all days with triptan intake independent of whether there was an effective response reduced the number of total migraine days with 5.2% (n = 100,905 days vs n=106,430 days). Figure 5 shows the number of migraine days where a triptan was used (43.4%, n=46,094 days) compared to the subset of these days (27.1%, n=28,804 days) with an effective response. Figure 5. Migraine days based on typical migraine characteristics with a duration of ≥ 4 hours (85.9%) vs days defined by triptan intake, divided in effective triptan response (27.1%) or all triptan intake (43.3%) for all patients (n = 1,494). A triptan was considered effective if the headache was reduced from moderate or severe to mild or no-pain within 2 hours post-dose. Change in number of monthly migraine days Table 3 shows the number of MMD as result of the use of different migraine day definitions. The use of our baseline definition resulted in a mean ± SD of 6.9 ± 4.9 MMD in all patients. By adjustment of the headache duration criterion to ≥ 30 minutes and including all days with triptan intake as migraine days resulted in a mean ± SD of 7.4 ± 5.1 MMD. The numbers of mean MMD with the different definitions for the subgroups of CM, HFEM and LFEM patients are shown in Table 3.
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