69 Defining migraine days 3 Differences between CM, HFEM and LFEM The ratio between migraine days matching migraine characteristics and those defined by triptan intake alone differed between CM, HFEM and LFEM patients (p < 0.001) (Table 3). For CM patients in particular, the majority of days (95.2%) matched the typical migraine characteristics. For HFEM and LFEM this was 78.7% and 74.0% respectively. Headache duration was the most common missing factor for CM (58.5%) and HFEM (71.3%). For LFEM patients, nausea/vomiting or photophobia/phonophobia was most often missing (82.8%), whereas headache duration of ≥4 hours was missing in 26.3% of days (Supplementary Figure 1). There was a strong, positive linear correlation (r = 0.94, p < .001) between the number of MMD (baseline definition) and the relative number of migraine days matching all migraine criteria (without days only defined by triptan intake). Figure 4 shows the linear regression line with a slope of 3.64 ± 0.034. Figure 4. Percentage of migraine days matching the typical characteristics for migraine (with a duration of ≥ 4 hours) shows a positive correlation with the total number of migraine days per patient using our baseline definition (≥ 4 hours and all triptan intake). In red the linear regression line fitted on the data.
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