23 General introduction 1 Figure 5c. Treatment of recurrences in perimenstrual attacks – adding a longacting NSAID Figure 5d. Treatment of recurrences in perimenstrual attacks – switching to a longer-acting triptan and moderately effective, and the initial response is often insufficient. If triptans or lasmiditan fail, gepants are now a viable substitute. Their relatively long half-life may contribute to sustained effects lasting up to 48 hours post-dose.51 However, there is limited data on the incidence of recurrence with gepants.
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