5 The effectiveness of a nation-wide implemented fall prevention intervention in the Netherlands | 87 Figure 5.3. Forest plot showing an overview of all outcome measures. RE = Relative Effect: intervention group regarding control group. The RE is calculated as the ratio of the change from baseline to the respective time point (M4 or M12) in the intervention group compared to the control group. The overall RE is computed as a weighted average of the REs at M4 and M12, proportional to the duration of each period. Process outcomes Adverse events No severe adverse events were reported that were related to the intervention or control group or the measurements during this study. Intervention adherence Participants attended a mean of 15.5 out of the 24 In Balance sessions, including study drop-outs. Of the 131 participants randomized in the intervention group, 15 participants (11.5%) dropped out of the In Balance intervention. Excluding the intervention drop-outs, the mean number of attended sessions was 17.9. Non-dropouts of the In Balance group had a mean MMSE-score of 28 (SD: 2.0) and this was 26 (SD: 3.5) for dropouts of the In Balance group. Moreover, 67% of the non-dropouts was non-frail, and this was 92% of the dropouts. DISCUSSION In this effectiveness analysis of the In Balance intervention program, as implemented routinely in non- and pre-frail community-dwelling older adults, we observed statistically non-significant differences in the number of falls, fall related injuries, balance, mobility, and quality of life, except for the mean number of fall injuries in the non-frail group and the TUG in the
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