114 | Chapter 6 by In Balance compared to the control became smaller in the per-protocol analysis (0.05) compared to the main analysis (0.28), the number of prevented fall-related injuries in the two analyses was similar. The difference in QALYs was similar in the per protocol and main analyses, although the difference in QALYs based on the ASCOT became statistically significant in the per protocol analysis. The probability of cost-effectiveness at a WTP of €0 per unit of effect gained (97%) was similar to the main analysis (98%). The cost difference from the healthcare perspective (€-2,700 (95% CI:- 7,020; 1,619) was smaller than the difference from the societal perspective (€-3,991) while the effect differences were the same. As a result, the probability of cost-effectiveness from the healthcare perspective compared to the societal perspective was lower (93% vs 98%, respectively) at a WTP threshold of €0 per unit of effect gained.
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