93 Quality assessment of patient reported outcome measures for patients with multiple ear complaints 5 Table 3: Content Validity assessment Content Validity Pilot test PROM Asking patients Asking experts Relevance Comprehensiveness Comprehensibility Relevance Comprehensiveness Meniere’s Disease Patient Oriented Symptom-Severity Index D D D A A no Chronic Otitis Media Questionnaire-12 A A A A A yes Cambridge Otology Quality of Life Questionnaire A V V A V yes Penn Acoustic Neuroma Quality of Life Scale A A I A A no Eustachian Tube Dysfunction Questionnaire A V V A A yes Chronic Ear Survey I I I D D no Otology Questionnaire Amsterdam V V A A A yes Meniere’s Disease Outcome Questionnaire I I I D D no The Gopen-Yang Superior Semicircular Canal Dehiscence Questionnaire D* D* D* D D no Dokuz Eylül University Meniere’s Disease Disability Scale I I I A A no Zurich Chronic Middle Ear Inventory D D I A A yes Chronic Otitis Media Outcome Test 15 I I I V V yes Ratings were scored as ‘very good’ (V), ‘adequate’ (A), ‘doubtful’ (D), ‘inadequate’ (I) * Since this questionnaire was developed from another validated questionnaire, the assessment in the absence of patient interview(s) was graded as “Doubtful” instead of “Inadequate”. listed in table 2. Ten out of twelve questionnaire were designed as disease specific, developed for either Eustachian tube dysfunction17, Acoustic Neuroma18, Meniere’s disease19-21, Semi-circular canal dehiscence22 or Chronic Otitis Media15,23-25. The other
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