Thesis

36 Chapter 2 All well-established questionnaires (e.g., Tinnitus Handicap Inventory23, Dizziness Handicap Inventory24, Abbreviated Profile of Hearing Aid Benefit25 were present in our results. In order to guarantee quality, our methods were in line with internationally recommended standards [PRISMA (Additional file 1), COSMIN]. This concerns the construction of our search syntax, the involvement of a medical information specialist (JCFK), the consultation of at least the Embase and MEDLINE databases, and at least two reviewers at every critical stage of the process with the possibility to discuss selection difficulties in an expert team.26 The results of this study will provide a starting point for future research (e.g., regarding the psychometric properties of the questionnaires). The methodological quality of the development and validation of each included questionnaire and the quality of the measurement properties (see Additional file 3) of each questionnaire is a vast amount of data which will be assessed in forthcoming studies. This assessment will be done according to the COSMIN methodology for systematic reviews of patient-reported outcome measures.26 This constitutes the use of the COSMIN Risk of Bias checklist for the assessment of the methodological quality of the studies and the measurement properties of the included questionnaires. Furthermore, measurement properties will be rated against the updated criteria for good measurement properties. The modified Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach will be used for grading the quality of evidence of the reported outcomes on measurement properties. Conclusions The presented work has systematically organized the existing questionnaires in otology. Clinicians and researchers benefit from the presented comprehensive overview of questionnaires as this enhances questionnaire selection. The database search performed in this systematic mapping review is the largest any study on this topic has assessed. Nearly every otology questionnaire identified in previously performed (systematic) reviews is included in this overview. Some suggestions for future studies on questionnaire measurement properties are proposed to facilitate an evidence-based questionnaire selection process. Supplementary Information The online version contains additional online files, available at: https://doi.org/10.1186/s13643-021-01659-9. Acknowledgements We thank Nivetha Thabothanakrishnan, for her work as part of the database review team.

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