Thesis

61 frequently neglected by their healthcare providers. Moreover, studies investigating these aspects in sarcoidosis patients with SFN are scarce. Conclusion In patients with sarcoidosis, particularly when diagnosed with SFN, the prevalence of fatigue, pain, RLS, and cognitive impairment is high. The majority of patients with sarcoidosis suffered from fatigue and pain. More than half of sarcoidosis patients with SFN also suffered from RLS and cognitive impairment. Additionally, the severity of all those symptoms was higher in patients with SFN compared with sarcoidosis patients without SFN. Therefore, the prevalence as well as the associations between fatigue, pain, RLS and cognitive impairment should make clinicians aware of the fact that the focus should not only be on assessment of pain but also other symptoms that can negatively influence the quality of life of patients. Although most of these symptoms cannot be cured or adequately treated at the moment, some of them, such as RLS, might be. Finally, merely addressing and acknowledging these bothersome symptoms is of outmost importance for these patients. 64 3

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