Thesis

57 Figure 2 Prevalence of A) fatigue, B) pain, C) restless legs syndrome (RLS), and D) cognitive impairment. Distributions are displayed for three groups: healthy controls (HC), patients with sarcoidosis without small fiber neuropathy (No SFN) and patients with sarcoidosis with SFN. p-values were displayed as stars: *<0.05; **<0.01; ***<0.001; ****<0.0001. Severity Overall, patients with sarcoidosis showed higher scores on the FAS, VASmean, VASmax (p=0.009 & p=8.4*10-11 resp. for patients with sarcoidosis without and with SFN) for patients with sarcoidosis, RLS, and CFQ than healthy controls. Moreover, within the group of sarcoidosis patients, patients with SFN showed more fatigue, mean pain, max pain (p=5.3*10-6) and RLS compared to patients without SFN (Figure 3). 3 60 3

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